Investigating Peptide‐Coenzyme A Conjugates as Chemical Probes for Proteomic Profiling of N‐Terminal and Lysine Acetyltransferases

Acetyl groups are transferred from acetyl‐coenzyme A (Ac‐CoA) to protein N‐termini and lysine side chains by N‐terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine‐CoA conjugates as KAT probes, we have synthesized peptide probes with CoA conjugate...

Descripción completa

Detalles Bibliográficos
Autores principales: Sindlinger, Julia, Schön, Stefan, Eirich, Jürgen, Kirchgäßner, Sören, Finkemeier, Iris, Schwarzer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541820/
https://www.ncbi.nlm.nih.gov/pubmed/35776679
http://dx.doi.org/10.1002/cbic.202200255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541820/
https://www.ncbi.nlm.nih.gov/pubmed/35776679
http://dx.doi.org/10.1002/cbic.202200255

Ejemplares similares