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Investigating Peptide‐Coenzyme A Conjugates as Chemical Probes for Proteomic Profiling of N‐Terminal and Lysine Acetyltransferases

Acetyl groups are transferred from acetyl‐coenzyme A (Ac‐CoA) to protein N‐termini and lysine side chains by N‐terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine‐CoA conjugates as KAT probes, we have synthesized peptide probes with CoA conjugate...

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Detalles Bibliográficos
Autores principales:	Sindlinger, Julia, Schön, Stefan, Eirich, Jürgen, Kirchgäßner, Sören, Finkemeier, Iris, Schwarzer, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541820/ https://www.ncbi.nlm.nih.gov/pubmed/35776679 http://dx.doi.org/10.1002/cbic.202200255

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