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Clinical Pharmacology of Insulin Aspart Biosimilar GP40071: Pharmacokinetic/Pharmacodynamic Comparability in Hyperinsulinemic Euglycemic Clamp Procedure

Insulin aspart is a short‐acting insulin analogue that is used to control postprandial glycemia levels in diabetic patients. The aim of this clinical trial was to compare the pharmacokinetics and pharmacodynamics of GP40071 (GP‐Asp) and NovoRapid Penfill (Novo‐Asp) in a hyperinsulinemic euglycemic c...

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Detalles Bibliográficos
Autores principales: Drai, Roman V., Karonova, Tatiana L., Mayorov, Alexander Y., Makarenko, Igor E., Dorotenko, Artem R., Kulesh, Viktoria S., Kovalik, Vladislav V., Andreeva, Alena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541865/
https://www.ncbi.nlm.nih.gov/pubmed/35230749
http://dx.doi.org/10.1002/cpdd.1084