The effect of duloxetine on mechanistic pain profiles, cognitive factors and clinical pain in patients with painful knee osteoarthritis—A randomized, double‐blind, placebo‐controlled, crossover study

BACKGROUND: Duloxetine is indicated in the management of pain in osteoarthritis. Evidence suggests that duloxetine modulates central pain mechanisms and cognitive factors, and these factors are assumed contributing to the analgesic effect. This proof‐of‐mechanism, randomized, placebo‐controlled, cro...

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Detalles Bibliográficos
Autores principales: Petersen, Kristian Kjær‐Staal, Drewes, Asbjørn Mohr, Olesen, Anne Estrup, Ammitzbøll, Nadia, Bertoli, Davide, Brock, Christina, Arendt‐Nielsen, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541875/
https://www.ncbi.nlm.nih.gov/pubmed/35638317
http://dx.doi.org/10.1002/ejp.1988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541875/
https://www.ncbi.nlm.nih.gov/pubmed/35638317
http://dx.doi.org/10.1002/ejp.1988

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