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The effect of duloxetine on mechanistic pain profiles, cognitive factors and clinical pain in patients with painful knee osteoarthritis—A randomized, double‐blind, placebo‐controlled, crossover study
BACKGROUND: Duloxetine is indicated in the management of pain in osteoarthritis. Evidence suggests that duloxetine modulates central pain mechanisms and cognitive factors, and these factors are assumed contributing to the analgesic effect. This proof‐of‐mechanism, randomized, placebo‐controlled, cro...
Autores principales: | Petersen, Kristian Kjær‐Staal, Drewes, Asbjørn Mohr, Olesen, Anne Estrup, Ammitzbøll, Nadia, Bertoli, Davide, Brock, Christina, Arendt‐Nielsen, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541875/ https://www.ncbi.nlm.nih.gov/pubmed/35638317 http://dx.doi.org/10.1002/ejp.1988 |
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