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DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling

Few cytokines/growth modulating proteins are known to be chemoattractants for hematopoietic stem (HSC) and progenitor cells (HPC); stromal cell‐derived factor 1α (SDF1α/CXCL12) being the most potent known such protein. DEK, a nuclear DNA‐binding chromatin protein with hematopoietic cytokine‐like act...

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Detalles Bibliográficos
Autores principales: Capitano, Maegan L., Sammour, Yasser, Ropa, James, Legendre, Maureen, Mor‐Vaknin, Nirit, Markovitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9541944/
https://www.ncbi.nlm.nih.gov/pubmed/35137444
http://dx.doi.org/10.1002/JLB.3AB1120-740R