Sirtuin 6 protects against hepatic fibrogenesis by suppressing the YAP and TAZ function

Hepatic fibrosis occurs in response to prolonged tissue injury in the liver, which results in abnormal accumulation of extracellular matrix. Hepatic stellate cells (HSCs) have been suggested to play a major role in liver fibrosis. However, the molecular mechanisms remain incompletely understood. Sir...

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Detalles Bibliográficos
Autores principales: Chowdhury, Kushan, Huang, Menghao, Kim, Hyeong‐Geug, Dong, X. Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542050/
https://www.ncbi.nlm.nih.gov/pubmed/36036554
http://dx.doi.org/10.1096/fj.202200522R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542050/
https://www.ncbi.nlm.nih.gov/pubmed/36036554
http://dx.doi.org/10.1096/fj.202200522R

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