Antigen receptor‐engineered Tregs inhibit CNS autoimmunity in cell therapy using nonredundant immune mechanisms in mice

CD4(+)FOXP3(+) Tregs are currently explored to develop cell therapies against immune‐mediated disorders, with an increasing focus on antigen receptor‐engineered Tregs. Deciphering their mode of action is necessary to identify the strengths and limits of this approach. Here, we addressed this issue i...

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Detalles Bibliográficos
Autores principales: Pohar, Jelka, O'Connor, Richard, Manfroi, Benoît, El‐Behi, Mohamed, Jouneau, Luc, Boudinot, Pierre, Bunse, Mario, Uckert, Wolfgang, Luka, Marine, Ménager, Mickael, Liblau, Roland, Anderton, Stephen M., Fillatreau, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542066/
https://www.ncbi.nlm.nih.gov/pubmed/35579560
http://dx.doi.org/10.1002/eji.202249845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542066/
https://www.ncbi.nlm.nih.gov/pubmed/35579560
http://dx.doi.org/10.1002/eji.202249845

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