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Antigen receptor‐engineered Tregs inhibit CNS autoimmunity in cell therapy using nonredundant immune mechanisms in mice
CD4(+)FOXP3(+) Tregs are currently explored to develop cell therapies against immune‐mediated disorders, with an increasing focus on antigen receptor‐engineered Tregs. Deciphering their mode of action is necessary to identify the strengths and limits of this approach. Here, we addressed this issue i...
Autores principales: | Pohar, Jelka, O'Connor, Richard, Manfroi, Benoît, El‐Behi, Mohamed, Jouneau, Luc, Boudinot, Pierre, Bunse, Mario, Uckert, Wolfgang, Luka, Marine, Ménager, Mickael, Liblau, Roland, Anderton, Stephen M., Fillatreau, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542066/ https://www.ncbi.nlm.nih.gov/pubmed/35579560 http://dx.doi.org/10.1002/eji.202249845 |
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