Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents

The group of 18 new amide derivatives of mycophenolic acid (MPA) and selected heterocyclic amines was synthesised as potential immunosuppressive agents functioning as inosine-5′-monophosphate dehydrogenase (IMPDH) uncompetitive inhibitors. The synthesis of 14 of them employed uronium-type activating...

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Detalles Bibliográficos
Autores principales: Walczak, Juliusz Maksymilian, Iwaszkiewicz-Grześ, Dorota, Ziomkowska, Michalina, Śliwka-Kaszyńska, Magdalena, Daśko, Mateusz, Trzonkowski, Piotr, Cholewiński, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542285/
https://www.ncbi.nlm.nih.gov/pubmed/36189734
http://dx.doi.org/10.1080/14756366.2022.2127701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542285/
https://www.ncbi.nlm.nih.gov/pubmed/36189734
http://dx.doi.org/10.1080/14756366.2022.2127701

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