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Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents
The group of 18 new amide derivatives of mycophenolic acid (MPA) and selected heterocyclic amines was synthesised as potential immunosuppressive agents functioning as inosine-5′-monophosphate dehydrogenase (IMPDH) uncompetitive inhibitors. The synthesis of 14 of them employed uronium-type activating...
Autores principales: | Walczak, Juliusz Maksymilian, Iwaszkiewicz-Grześ, Dorota, Ziomkowska, Michalina, Śliwka-Kaszyńska, Magdalena, Daśko, Mateusz, Trzonkowski, Piotr, Cholewiński, Grzegorz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542285/ https://www.ncbi.nlm.nih.gov/pubmed/36189734 http://dx.doi.org/10.1080/14756366.2022.2127701 |
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