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Cytosolic dsRNA improves neonatal innate immune responses to adjuvants in use in pediatric vaccines

Pattern recognition receptors (PRRs) of the innate immune system represent the critical front‐line defense against pathogens, and new vaccine formulations target these PRR pathways to boost vaccine responses, through activation of cellular/Th1 immunity. The majority of pediatric vaccines contain alu...

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Detalles Bibliográficos
Autores principales: Brennan, Kiva, Craven, Simon, Cheung, Maria, Kane, Daniel, Noone, Eleanor, O'Callaghan, Joseph, Molloy, Eleanor J, Walsh, Patrick T, McAuliffe, Fionnuala M, Doyle, Sarah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542317/
https://www.ncbi.nlm.nih.gov/pubmed/35098572
http://dx.doi.org/10.1002/JLB.5A0521-242R