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Activation of GRP78 ATPase suppresses A549 lung cancer cell migration by promoting ITGB4 degradation

Hypochlorous acid (HOCl) is an essential signal molecule in cancer cells. Activated GRP78 ATPase by a HOCl probe named ZBM-H inhibits lung cancer cell growth. However, the role and underlying mechanism of GRP78 ATPase in lung cancer cell migration have not been established. Here, we reported that ac...

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Detalles Bibliográficos
Autores principales: Ning, Junya, Cui, Xiaoling, Li, Nan, Li, Na, Zhao, Baoxiang, Miao, Junying, Lin, Zhaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542429/
https://www.ncbi.nlm.nih.gov/pubmed/36203272
http://dx.doi.org/10.1080/19336918.2022.2130415