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Lung adenocarcinoma harboring complex EML4-ALK fusion and BRAF V600E co-mutation responded to alectinib

The echinoderm microtubule-associated protein-like 4 gene and anaplastic lymphoma kinase gene (EML4-ALK) is the most frequent fusion variant of ALK rearrangements in non-small cell lung cancer (NSCLC). With the widespread application of next-generation sequencing (NGS), more fusions and co-mutations...

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Detalles Bibliográficos
Autores principales: Guo, Weihong, Liang, Jianping, Zhang, Dandan, Huang, Xikun, Lv, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542562/
https://www.ncbi.nlm.nih.gov/pubmed/36221356
http://dx.doi.org/10.1097/MD.0000000000030913