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Chaperone-mediated autophagy protects against atherosclerosis

Atherosclerosis, the leading cause of cardiovascular death, is driven by hyperlipidemia, inflammation and aggravated by aging. As chaperone-mediated autophagy (CMA), a selective type of lysosomal degradation for intracellular proteins, diminishes with age and is inhibited by lipid excess, we studied...

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Detalles Bibliográficos
Autores principales: Madrigal-Matute, Julio, Cuervo, Ana Maria, Sluimer, Judith C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542634/
https://www.ncbi.nlm.nih.gov/pubmed/35787098
http://dx.doi.org/10.1080/15548627.2022.2096397