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Chaperone-mediated autophagy protects against atherosclerosis
Atherosclerosis, the leading cause of cardiovascular death, is driven by hyperlipidemia, inflammation and aggravated by aging. As chaperone-mediated autophagy (CMA), a selective type of lysosomal degradation for intracellular proteins, diminishes with age and is inhibited by lipid excess, we studied...
Autores principales: | Madrigal-Matute, Julio, Cuervo, Ana Maria, Sluimer, Judith C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542634/ https://www.ncbi.nlm.nih.gov/pubmed/35787098 http://dx.doi.org/10.1080/15548627.2022.2096397 |
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