Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine

[Image: see text] Miltefosine is a repurposed anticancer drug and currently the only orally administered drug approved to treat the neglected tropical disease leishmaniasis. Miltefosine is hygroscopic and must be stored at subzero temperatures. In this work, we report the X-ray structures of miltefo...

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Detalles Bibliográficos
Autores principales: Hall, Amy V., Gostick, Isobel E. F., Yufit, Dmitry S., Marchant, Gloria Y., Kirubakaran, Preyanthiny, Madu, Shadrack J., Li, Mingzhong, Steel, Patrick G., Steed, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542694/
https://www.ncbi.nlm.nih.gov/pubmed/36217416
http://dx.doi.org/10.1021/acs.cgd.2c00843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542694/
https://www.ncbi.nlm.nih.gov/pubmed/36217416
http://dx.doi.org/10.1021/acs.cgd.2c00843

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