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Integral Role of Water in the Solid-State Behavior of the Antileishmanial Drug Miltefosine
[Image: see text] Miltefosine is a repurposed anticancer drug and currently the only orally administered drug approved to treat the neglected tropical disease leishmaniasis. Miltefosine is hygroscopic and must be stored at subzero temperatures. In this work, we report the X-ray structures of miltefo...
Autores principales: | Hall, Amy V., Gostick, Isobel E. F., Yufit, Dmitry S., Marchant, Gloria Y., Kirubakaran, Preyanthiny, Madu, Shadrack J., Li, Mingzhong, Steel, Patrick G., Steed, Jonathan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542694/ https://www.ncbi.nlm.nih.gov/pubmed/36217416 http://dx.doi.org/10.1021/acs.cgd.2c00843 |
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