Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation

[Image: see text] Long-acting injectables are a unique drug formulation strategy, providing a slow and sustained release of active pharmaceutical ingredients (APIs). In this study, a novel approach that combines liquid antisolvent precipitation with seeding to obtain a stable form of the API indomet...

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Detalles Bibliográficos
Autores principales: Hugo Silva, Mariana, Kumar, Ajay, Hodnett, Benjamin K., Tajber, Lidia, Holm, René, Hudson, Sarah P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542716/
https://www.ncbi.nlm.nih.gov/pubmed/36217420
http://dx.doi.org/10.1021/acs.cgd.2c00678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542716/
https://www.ncbi.nlm.nih.gov/pubmed/36217420
http://dx.doi.org/10.1021/acs.cgd.2c00678

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