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Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation
[Image: see text] Long-acting injectables are a unique drug formulation strategy, providing a slow and sustained release of active pharmaceutical ingredients (APIs). In this study, a novel approach that combines liquid antisolvent precipitation with seeding to obtain a stable form of the API indomet...
Autores principales: | Hugo Silva, Mariana, Kumar, Ajay, Hodnett, Benjamin K., Tajber, Lidia, Holm, René, Hudson, Sarah P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542716/ https://www.ncbi.nlm.nih.gov/pubmed/36217420 http://dx.doi.org/10.1021/acs.cgd.2c00678 |
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