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Could Amyloid-β 1–42 or α-Synuclein Interact Directly with Mitochondrial DNA? A Hypothesis

[Image: see text] The amyloid β (Aβ) and the α-synuclein (α-syn) are shown to be translocated into mitochondria. Even though their roles are widely investigated in pathological conditions, information on the presence and functions of Aβ and α-syn in mitochondria in endogenous levels is somewhat limi...

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Detalles Bibliográficos
Autores principales: Gezen-Ak, Duygu, Yurttaş, Zuhal, Çamoǧlu, Tugay, Dursun, Erdinç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542719/
https://www.ncbi.nlm.nih.gov/pubmed/36125124
http://dx.doi.org/10.1021/acschemneuro.2c00512