Catalytic Stereoconvergent Synthesis of Homochiral β-CF(3), β-SCF(3), and β-OCF(3) Benzylic Alcohols

[Image: see text] We describe an efficient catalytic strategy for enantio- and diastereoselective synthesis of homochiral β-CF(3), β-SCF(3), and β-OCF(3) benzylic alcohols. The approach is based on dynamic kinetic resolution (DKR) with Noyori–Ikariya asymmetric transfer hydrogenation leading to simu...

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Detalles Bibliográficos
Autores principales: Cotman, Andrej Emanuel, Dub, Pavel A., Sterle, Maša, Lozinšek, Matic, Dernovšek, Jaka, Zajec, Živa, Zega, Anamarija, Tomašič, Tihomir, Cahard, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542724/
https://www.ncbi.nlm.nih.gov/pubmed/36217345
http://dx.doi.org/10.1021/acsorginorgau.2c00019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542724/
https://www.ncbi.nlm.nih.gov/pubmed/36217345
http://dx.doi.org/10.1021/acsorginorgau.2c00019

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