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Exercise and hypoxia unmask pulmonary vascular disease and right ventricular dysfunction in a 10‐ to 12‐week‐old swine model of neonatal oxidative injury

ABSTRACT: Prematurely born young adults who experienced neonatal oxidative injury (NOI) of the lungs have increased incidence of cardiovascular disease. Here, we investigated the long‐term effects of NOI on cardiopulmonary function in piglets at the age of 10–12 weeks. To induce NOI, term‐born pigle...

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Detalles Bibliográficos
Autores principales: Steenhorst, Jarno J., Hirsch, Alexander, Verzijl, Annemarie, Wielopolski, Piotr, de Wijs‐Meijler, Daphne, Duncker, Dirk J., Reiss, Irwin K. M., Merkus, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542957/
https://www.ncbi.nlm.nih.gov/pubmed/35862359
http://dx.doi.org/10.1113/JP282906