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An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes

Vitamin B12 has multiple biochemical functions including in the one-carbon cycle generating a methyl group for DNA methylation, and metabolism of fatty acids and amino acids to generate energy via the citric acid cycle. The aim of our study was to use a combined epigenomic and transcriptomic approac...

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Detalles Bibliográficos
Autores principales: Ogunkolade, B. William, Adaikalakoteswari, Antonysunil, Cardoso, Shirleny Romualdo, Lowe, Rob, Patel, Nisha, Rakyan, Vardhman, Finer, Sarah, Wabitsch, Martin, Saravanan, Ponnusamy, Tripathi, Gyanendra, Bochukova, Elena, Hitman, Graham A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9542961/
https://www.ncbi.nlm.nih.gov/pubmed/34818986
http://dx.doi.org/10.1080/15592294.2021.2003043