BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes

Acute myeloid leukemia (AML) is a highly cancerous and aggressive hematologic disease with elevated levels of drug resistance and relapse resulting in high mortality. Recently, bromodomains and extra-terminal (BET) protein inhibitors have been extensively researched in hematological tumors as potent...

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Detalles Bibliográficos
Autores principales: Ma, Li, Wang, Jianwei, Zhang, Yongping, Fang, Fang, Ling, Jing, Chu, Xinran, Zhang, Zimu, Tao, Yanfang, Li, Xiaolu, Tian, Yuanyuan, Li, Zhiheng, Sang, Xu, Zhang, Kunlong, Lu, Lihui, Wan, Xiaomei, Chen, Yanling, Yu, Juanjuan, Zhuo, Ran, Wu, Shuiyan, Lu, Jun, Pan, Jian, Hu, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543111/
https://www.ncbi.nlm.nih.gov/pubmed/36170346
http://dx.doi.org/10.1080/15384047.2022.2125748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543111/
https://www.ncbi.nlm.nih.gov/pubmed/36170346
http://dx.doi.org/10.1080/15384047.2022.2125748

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