Total Synthesis of Ophiorrhine A, G and Ophiorrhiside E Featuring a Bioinspired Intramolecular Diels–Alder Cycloaddition

We report the first total synthesis of the monoterpene indole alkaloids ophiorrhine A via a late stage bioinspired intramolecular Diels–Alder cycloaddition to form the intricate bridged and spirannic polycyclic system. Several strategies were investigated to construct the indolopyridone moiety of op...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Wei, Dou, Yingchao, Kouklovsky, Cyrille, Vincent, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543224/
https://www.ncbi.nlm.nih.gov/pubmed/35869029
http://dx.doi.org/10.1002/anie.202209135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543224/
https://www.ncbi.nlm.nih.gov/pubmed/35869029
http://dx.doi.org/10.1002/anie.202209135

Ejemplares similares