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Total Synthesis of Ophiorrhine A, G and Ophiorrhiside E Featuring a Bioinspired Intramolecular Diels–Alder Cycloaddition

We report the first total synthesis of the monoterpene indole alkaloids ophiorrhine A via a late stage bioinspired intramolecular Diels–Alder cycloaddition to form the intricate bridged and spirannic polycyclic system. Several strategies were investigated to construct the indolopyridone moiety of op...

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Detalles Bibliográficos
Autores principales:	Cao, Wei, Dou, Yingchao, Kouklovsky, Cyrille, Vincent, Guillaume
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543224/ https://www.ncbi.nlm.nih.gov/pubmed/35869029 http://dx.doi.org/10.1002/anie.202209135

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