Dissecting the impact of bromodomain inhibitors on the Interferon Regulatory Factor 4‐MYC oncogenic axis in multiple myeloma

B‐cell progenitor fate determinant interferon regulatory factor 4 (IRF4) exerts key roles in the pathogenesis and progression of multiple myeloma (MM), a currently incurable plasma cell malignancy. Aberrant expression of IRF4 and the establishment of a positive auto‐regulatory loop with oncogene MYC...

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Detalles Bibliográficos
Autores principales: Agnarelli, Alessandro, Mitchell, Simon, Caalim, Gillian, Wood, C. David, Milton‐Harris, Leanne, Chevassut, Timothy, West, Michelle J., Mancini, Erika J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543246/
https://www.ncbi.nlm.nih.gov/pubmed/35544413
http://dx.doi.org/10.1002/hon.3016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543246/
https://www.ncbi.nlm.nih.gov/pubmed/35544413
http://dx.doi.org/10.1002/hon.3016

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