A Desilylative Approach to Alkyl Substituted C(1)‐Ammonium Enolates: Application in Enantioselective [2+2] Cycloadditions

The catalytic generation of C(1)‐ammonium enolates from the corresponding α‐silyl‐α‐alkyl substituted carboxylic acids using the isothiourea HyperBTM is reported. This desilylative approach grants access to α‐unsubstituted and α‐alkyl substituted C(1)‐ammonium enolates, which are typically difficult...

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Detalles Bibliográficos
Autores principales: Wang, Yihong, Young, Claire M., Liu, Honglei, Hartley, Will C., Wienhold, Max, Cordes, David. B., Slawin, Alexandra M. Z., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543305/
https://www.ncbi.nlm.nih.gov/pubmed/35833471
http://dx.doi.org/10.1002/anie.202208800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543305/
https://www.ncbi.nlm.nih.gov/pubmed/35833471
http://dx.doi.org/10.1002/anie.202208800

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