Population pharmacokinetics of cabotegravir following administration of oral tablet and long‐acting intramuscular injection in adult HIV‐1‐infected and uninfected subjects

AIM: To characterize cabotegravir population pharmacokinetics using data from phase 1, 2 and 3 studies and evaluate the association of intrinsic and extrinsic factors with pharmacokinetic variability. METHODS: Analyses were implemented in NONMEM and R. Concentrations below the quantitation limit wer...

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Detalles Bibliográficos
Autores principales: Han, Kelong, Baker, Mark, Lovern, Mark, Paul, Prokash, Xiong, Yuan, Patel, Parul, Moore, Katy P., Seal, Ciara S., Cutrell, Amy G., D'Amico, Ronald D., Benn, Paul D., Landovitz, Raphael J., Marzinke, Mark A., Spreen, William R., Ford, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543358/
https://www.ncbi.nlm.nih.gov/pubmed/35695476
http://dx.doi.org/10.1111/bcp.15439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543358/
https://www.ncbi.nlm.nih.gov/pubmed/35695476
http://dx.doi.org/10.1111/bcp.15439

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