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Dihydroartemisinin protects blood–brain barrier permeability during sepsis by inhibiting the transcription factor SNAI1

Blood–brain barrier (BBB) injury is involved in the pathogenesis of sepsis‐associated encephalopathy. In this study, we used dihydroartemisinin (DHA), a derivative of artemisinin, to treat a cecal ligation and puncture (CLP)‐induced mouse sepsis model and a tumour necrosis factor α (TNF‐α)‐stimulate...

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Detalles Bibliográficos
Autores principales: Liu, Fuhong, Liu, Jing, Xiang, Hongjie, Sun, Zongguo, Li, Yan, Li, Xiao, Liu, Yanjun, Liu, Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543489/
https://www.ncbi.nlm.nih.gov/pubmed/35651290
http://dx.doi.org/10.1111/1440-1681.13683