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Contribution of haemodynamic side effects and associated autonomic reflexes to ventricular arrhythmias triggering by torsadogenic hERG blocking drugs

BACKGROUND AND PURPOSE: HERG blocking drugs known for their propensity to trigger Torsades de Pointes (TdP) were reported to induce a sympatho‐vagal coactivation and to enhance High Frequency heart rate (HFHR) and QT oscillations (HFQT) in telemetric data. The present work aimed to characterize the...

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Detalles Bibliográficos
Autores principales: Champéroux, Pascal, Fares, Raafat, Bastogne, Thierry, Richard, Serge, Le Guennec, Jean‐Yves, Thireau, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543494/
https://www.ncbi.nlm.nih.gov/pubmed/35751378
http://dx.doi.org/10.1111/bph.15905