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Contribution of haemodynamic side effects and associated autonomic reflexes to ventricular arrhythmias triggering by torsadogenic hERG blocking drugs
BACKGROUND AND PURPOSE: HERG blocking drugs known for their propensity to trigger Torsades de Pointes (TdP) were reported to induce a sympatho‐vagal coactivation and to enhance High Frequency heart rate (HFHR) and QT oscillations (HFQT) in telemetric data. The present work aimed to characterize the...
Autores principales: | Champéroux, Pascal, Fares, Raafat, Bastogne, Thierry, Richard, Serge, Le Guennec, Jean‐Yves, Thireau, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543494/ https://www.ncbi.nlm.nih.gov/pubmed/35751378 http://dx.doi.org/10.1111/bph.15905 |
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