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Lack of clinically relevant differences in safety and pharmacokinetics after second‐dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis

OBJECTIVE: Current diazepam nasal spray labeling requires waiting 4 h before administering a second dose. The objective of the current analyses was to examine safety and pharmacokinetic profiles of second doses of diazepam nasal spray given 0−4 h after the first dose. METHODS: Two datasets were anal...

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Detalles Bibliográficos
Autores principales: Cascino, Gregory D., Tarquinio, Daniel, Wheless, James W., Hogan, Robert Edward, Sperling, Michael R., Desai, Jay, Vazquez, Blanca, Samara, Emil, Misra, Sunita N., Carrazana, Enrique, Rabinowicz, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543781/
https://www.ncbi.nlm.nih.gov/pubmed/35377464
http://dx.doi.org/10.1111/epi.17249