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The C‐terminal head domain of Burkholderia pseudomallei BpaC has a striking hydrophilic core with an extensive solvent network

Gram‐negative pathogens like Burkholderia pseudomallei use trimeric autotransporter adhesins such as BpaC as key molecules in their pathogenicity. Our 1.4 Å crystal structure of the membrane‐proximal part of the BpaC head domain shows that the domain is exclusively made of left‐handed parallel β‐rol...

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Detalles Bibliográficos
Autores principales: Kiessling, Andreas R., Harris, Sarah A., Weimer, Kathleen M., Wells, Geoffrey, Goldman, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543794/
https://www.ncbi.nlm.nih.gov/pubmed/35703459
http://dx.doi.org/10.1111/mmi.14953