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The cation channel TRPM8 influences the differentiation and function of human monocytes

Monocytes are mononuclear phagocytes that can differentiate to a variety of cell fates under the influence of their microenvironment and hardwired commitment. We found that inhibition of TRPM8 in human blood CD14(+) monocytes during a critical 3‐h window at the beginning of their differentiation int...

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Detalles Bibliográficos
Autores principales: Hornsby, Eve, King, Hamish W., Peiris, Madusha, Buccafusca, Roberto, Lee, Wing‐Yiu Jason, Wing, Elinor S., Blackshaw, L. Ashley, Lindsay, James O., Stagg, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543907/
https://www.ncbi.nlm.nih.gov/pubmed/35233801
http://dx.doi.org/10.1002/JLB.1HI0421-181R