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Aptamer‐Array‐Guided Protein Assembly Enhances Synthetic mRNA Switch Performance

Synthetic messenger RNA (mRNA) switches are powerful synthetic biological tools that can sense cellular molecules to manipulate cell fate. However, their performances are limited by high output signal noise due to leaky output protein expression. Here, we designed a readout control module that disab...

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Detalles Bibliográficos
Autores principales: Lu, Qiuyu, Hu, Yaxin, Yin Li, Cheuk, Kuang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544043/
https://www.ncbi.nlm.nih.gov/pubmed/35703374
http://dx.doi.org/10.1002/anie.202207319