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Novel animal model of combined generalized and focal epilepsy

Thioredoxin, encoded by Txn1, is a critical antioxidant that protects against oxidative damage by regulating the dithiol/disulfide balance of interacting proteins. We recently discovered the Adem rat, an epileptic rat harboring the Txn1‐F54L mutation, characterized by wild running and vacuolar degen...

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Detalles Bibliográficos
Autores principales: Ohmori, Iori, Ouchida, Mamoru, Shinohara, Masakazu, Kobayashi, Kiyoka, Ishida, Saeko, Mashimo, Tomoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544055/
https://www.ncbi.nlm.nih.gov/pubmed/35532890
http://dx.doi.org/10.1111/epi.17295