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Novel animal model of combined generalized and focal epilepsy
Thioredoxin, encoded by Txn1, is a critical antioxidant that protects against oxidative damage by regulating the dithiol/disulfide balance of interacting proteins. We recently discovered the Adem rat, an epileptic rat harboring the Txn1‐F54L mutation, characterized by wild running and vacuolar degen...
Autores principales: | Ohmori, Iori, Ouchida, Mamoru, Shinohara, Masakazu, Kobayashi, Kiyoka, Ishida, Saeko, Mashimo, Tomoji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544055/ https://www.ncbi.nlm.nih.gov/pubmed/35532890 http://dx.doi.org/10.1111/epi.17295 |
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