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Effects of sildenafil on symptoms and exercise capacity for heart failure with reduced ejection fraction and pulmonary hypertension (the SilHF study): a randomized placebo‐controlled multicentre trial

AIMS: Pulmonary hypertension (PHT) may complicate heart failure with reduced ejection fraction (HFrEF) and is associated with a substantial symptom burden and poor prognosis. Sildenafil, a phosphodiesterase‐5 (PDE‐5) inhibitor, might have beneficial effects on pulmonary haemodynamics, cardiac functi...

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Detalles Bibliográficos
Autores principales: Cooper, Trond J., Cleland, John G.F., Guazzi, Marco, Pellicori, Pierpaolo, Ben Gal, Tuvia, Amir, Offer, Al‐Mohammad, Abdallah, Clark, Andrew L., McConnachie, Alex, Steine, Kjetil, Dickstein, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544113/
https://www.ncbi.nlm.nih.gov/pubmed/35596935
http://dx.doi.org/10.1002/ejhf.2527