Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain

Prion diseases are transmissible, neurodegenerative disorders associated with misfolding of the prion protein. Previous studies show that reduction of microglia accelerates central nervous system (CNS) prion disease and increases the accumulation of prions in the brain, suggesting that microglia pro...

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Detalles Bibliográficos
Autores principales: Bradford, Barry M., McGuire, Lynne I., Hume, David A., Pridans, Clare, Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544114/
https://www.ncbi.nlm.nih.gov/pubmed/35852018
http://dx.doi.org/10.1002/glia.24244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544114/
https://www.ncbi.nlm.nih.gov/pubmed/35852018
http://dx.doi.org/10.1002/glia.24244

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