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Alternative pathway for dopamine production by acetogenic gut bacteria that O‐Demethylate 3‐Methoxytyramine, a metabolite of catechol O‐Methyltransferase

AIMS: The gut microbiota modulates dopamine levels in vivo, but the bacteria and biochemical processes responsible remain incompletely characterized. A potential precursor of bacterial dopamine production is 3‐methoxytyramine (3MT); 3MT is produced when dopamine is O‐methylated by host catechol O‐me...

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Detalles Bibliográficos
Autores principales: Rich, Barry E., Jackson, Jayme C., de Ora, Lizett Ortiz, Long, Zane G., Uyeda, Kylie S., Bess, Elizabeth N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544265/
https://www.ncbi.nlm.nih.gov/pubmed/35737746
http://dx.doi.org/10.1111/jam.15682