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Partial Restoration of Brain Dystrophin and Behavioral Deficits by Exon Skipping in the Muscular Dystrophy X‐Linked (mdx) Mouse

OBJECTIVES: Duchenne muscular dystrophy is associated with various degrees of cognitive impairment and behavioral disturbances. Emotional and memory deficits also constitute reliable outcome measures to assess efficacy of treatments in the mdx mouse lacking the muscle and neuronal full‐length dystro...

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Detalles Bibliográficos
Autores principales: Zarrouki, Faouzi, Relizani, Karima, Bizot, Flavien, Tensorer, Thomas, Garcia, Luis, Vaillend, Cyrille, Goyenvalle, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544349/
https://www.ncbi.nlm.nih.gov/pubmed/35587226
http://dx.doi.org/10.1002/ana.26409