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Long access to cocaine self‐administration dysregulates the glutamate synapse in the nucleus accumbens core of serotonin transporter knockout rats

BACKGROUND AND PURPOSE: It is well established that the nucleus accumbens and glutamate play a critical role in the motivation to take drugs of abuse. We have previously demonstrated that rats with ablation of the serotonin (5‐HT) transporter (SERT(−/−) rats) show increased cocaine intake reminiscen...

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Detalles Bibliográficos
Autores principales: Caffino, Lucia, Mottarlini, Francesca, Targa, Giorgia, Verheij, Michel M. M., Homberg, Judith, Fumagalli, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544393/
https://www.ncbi.nlm.nih.gov/pubmed/33880773
http://dx.doi.org/10.1111/bph.15496