Functional antibody characterization via direct structural analysis and information‐driven protein–protein docking

Detailed description of the mechanism of action of the therapeutic antibodies is essential for the functional characterization and future optimization of potential clinical agents. We recently developed KD035, a fully human antibody targeting vascular endothelial growth factor receptor 2 (VEGFR2). K...

Descripción completa

Detalles Bibliográficos
Autores principales: Depetris, Rafael S., Lu, Dan, Polonskaya, Zhanna, Zhang, Zhikai, Luna, Xenia, Tankard, Amari, Kolahi, Pegah, Drummond, Michael, Williams, Chris, Ebert, Maximilian C. C. J. C., Patel, Jeegar P., Poyurovsky, Masha V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544432/
https://www.ncbi.nlm.nih.gov/pubmed/34773424
http://dx.doi.org/10.1002/prot.26280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544432/
https://www.ncbi.nlm.nih.gov/pubmed/34773424
http://dx.doi.org/10.1002/prot.26280

Ejemplares similares