Biosynthesis of Menaquinone in E. coli: Identification of an Elusive Isomer of SEPHCHC

In the biosynthesis of menaquinone in bacteria, the thiamine diphosphate‐dependent enzyme MenD catalyzes the decarboxylative carboligation of α‐ketoglutarate and isochorismate to (1R,2S,5S,6S)‐2‐succinyl‐5‐enolpyruvyl‐6‐hydroxycyclohex‐3‐ene‐1‐carboxylate (SEPHCHC). The regioisomer of SEPHCHC, namel...

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Detalles Bibliográficos
Autores principales: Fries, Alexander, Mazzaferro, Laura S., Bisel, Philippe, Hubrich, Florian, Andexer, Jennifer N., Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544450/
https://www.ncbi.nlm.nih.gov/pubmed/35901288
http://dx.doi.org/10.1002/cbic.202200181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544450/
https://www.ncbi.nlm.nih.gov/pubmed/35901288
http://dx.doi.org/10.1002/cbic.202200181

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