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A generalized robust allele‐based genetic association test

The allele‐based association test, comparing allele frequency difference between case and control groups, is locally most powerful. However, application of the classical allelic test is limited in practice, because the method is sensitive to the Hardy–Weinberg equilibrium (HWE) assumption, not appli...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544499/
https://www.ncbi.nlm.nih.gov/pubmed/33729547
http://dx.doi.org/10.1111/biom.13456