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A Novel Agnostic Respiratory Stimulant as a Treatment for Apnea of Prematurity: A Proof-of-Concept Study

Aim/Objective: ENA-001 is a novel selective antagonist of large-conductance BK (big potassium) channels located in the carotid bodies, where they act as chemoreceptors that sense low arterial oxygen levels and establish a feedback loop to brainstem nuclei responsible for initiating spontaneous breat...

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Detalles Bibliográficos
Autores principales: Miller, Thomas L, Raab, Lynn M, Shaffer, Thomas H, Schweikert, Alfred, Diana, Frank, Fort, Prem, Frum, Alana S, Pergolizzi, Joseph, Raffa, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544529/
https://www.ncbi.nlm.nih.gov/pubmed/36237747
http://dx.doi.org/10.7759/cureus.28900