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A Novel Agnostic Respiratory Stimulant as a Treatment for Apnea of Prematurity: A Proof-of-Concept Study
Aim/Objective: ENA-001 is a novel selective antagonist of large-conductance BK (big potassium) channels located in the carotid bodies, where they act as chemoreceptors that sense low arterial oxygen levels and establish a feedback loop to brainstem nuclei responsible for initiating spontaneous breat...
Autores principales: | Miller, Thomas L, Raab, Lynn M, Shaffer, Thomas H, Schweikert, Alfred, Diana, Frank, Fort, Prem, Frum, Alana S, Pergolizzi, Joseph, Raffa, Robert B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544529/ https://www.ncbi.nlm.nih.gov/pubmed/36237747 http://dx.doi.org/10.7759/cureus.28900 |
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