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Amplified Ca(2+) dynamics and accelerated cell proliferation in breast cancer tissue during purinergic stimulation

Intracellular Ca(2+) dynamics shape malignant behaviors of cancer cells. Whereas previous studies focused on cultured cancer cells, we here used breast organoids and colonic crypts freshly isolated from human and murine surgical biopsies. We performed fluorescence microscopy to evaluate intracellula...

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Detalles Bibliográficos
Autores principales: Henningsen, Mikkel B., McWhan, Kezia, Dam, Vibeke S., Mele, Marco, Hauerslev, Katrine R., Voss, Ninna C. S., Dabir, Parag D., Balling, Eva, Pedersen, Helene L., Vahl, Pernille, Johansen, Tonje, Tramm, Trine, Christiansen, Peer M., Boedtkjer, Ebbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9544627/
https://www.ncbi.nlm.nih.gov/pubmed/35657342
http://dx.doi.org/10.1002/ijc.34147